Fecal microbiome transplant
Simple, effective, safe, and natural.
Fecal transplantation (FMT) naturally counteracts the dysbiosis typically present in chronic enteropathies, repopulating and rebalancing the intestinal microbiome.
FMT made with freeze-dried capsules is simple and effective: the capsules are easy to transport, store and administer, and over 80% of chronic enteropathic dogs and cats respond positively.
Pet FMT Project
In Europe, fecal material cannot be placed on the market as a product. For this reason, EuBiome has structured the Pet FMT Project as a research project, under a protocol that received a favorable opinion from the OPBA (Animal Welfare Body) of the University of Padua. Participating veterinarians take part in the research; the material is provided as experimental material, and all clinical decisions remain the responsibility of the veterinarian, who acts under their own professional responsibility.
But there is more!
Participating means being part of a unique project in Europe, of a network that produces and exchanges knowledge and helps to understand the role of the microbiome in chronic enteropathies and make fecal transplantation ever more effective.
Over 300 vets have already joined!
Join us and offer this innovative solution to your clients too.
How to Participate in the Pet FMT Project
Agreement
Request and sign the project agreement
Consent
Inform and have the owner sign the consent
Data
Collect and send pet data
Payment
Buy the FMT Kit
How to do it
Do you want to participate?
Are you already affiliated?
Safety first
How We Manage Donors and Fecal Material
Donor requirement
- healthy from birth
- no pathologies
- between 1 and 6 years old
- regularly vaccinated
- no antibiotic use in the last 6 months, maximum one short antibiotic course in their lifetime
- no use of other medications
- no acute gastrointestinal episodes in the last 6 months
- no chronic gastrointestinal problems, atopic dermatitis, or abnormal behavior
Eligibility Evaluation
The eligibility evaluation process includes the following steps:- owner questionnaire
- microbiome analysis (must be compatible with the healthy reference population)
- stool analysis
- blood analysis
- medical examination
Maintaining Eligibility
Maintaining eligibility is an ongoing process throughout the period.The owner monitors the pet's health and fills out an online questionnaire weekly, and every month and a half, we reassess the stool. Any anomaly leads to the suspension of eligibility and the elimination of all collected material.
Material Management
The collected material is handled according to established protocols in the scientific literature to ensure optimal preservation of microbial viability, following good practices for the manipulation of biological material and with all necessary precautions to protect both the material and the operator. Once it arrives at the laboratory, it is pre-processed (dilution, filtration, addition of cryoprotectant) under a biological safety cabinet and placed in quarantine at –80 °C by specialized personnel who are properly trained and equipped to manage biological risk. Only if the analyses—repeated after the collection period—remain optimal, the material is released, lyophilized, and encapsulated. The resulting powder is characterized by NGS-16S sequencing, which serves both as a quality control measure and for subsequent evaluations of the donor microbiome engraftment.
FAQ
- Who are the recipients?
Dogs and cats with symptoms of chronic enteropathy for at least 3 weeks and atopic dermatitis. - Are there any exclusions?
- Enteropathies due to parasitosis, neoplasms, endocrinopathies, dysphagia, or age under 4 months.
- Dermatitis caused by parasites.
- Is FMT the last resort?
No!
The logic is that fecal transplantation aims to rebalance the microbiome, but if organs and tissues are severely compromised, FMT is unlikely to make a significant difference. - When to do FMT then?
More and more veterinarians suggest using fecal transplantation after the failure of dietary trials, possibly accompanied by drugs that reduce the inflammatory state. The sooner you intervene when dysbiosis is suspected, the better. - Is it necessary to stop other therapies?
Fecal transplantation is a treatment that can be combined with other therapeutic approaches available to the veterinarian, who is solely responsible for the therapy. We only suggest not using antibiotics and probiotics simultaneously, based on the logic that they may be potential competitors to the transplant itself. - What does the FMT kit contain?
30 capsules of lyophilized microbiome from healthy animals and 2 collection kits for microbiome analysis.At the end of the cycle, the FMT Report is returned, which shows the situation of the microbiome before and after the transplant and the possible contribution of the donor. Ask for a sample of the FMT Report. - How are the capsules administered?
According to the Pet FMT Project protocol, one capsule per day, administered orally, with a small treat if necessary. Administration can be adjusted based on the animal’s response (e.g., starting with one capsule every 2–3 days in animals that are particularly sensitive to dietary changes). -
What size are the capsules?
We provide size 4 capsules: diameter 5.3 mm and length 14.3 mm. - Can the administration be stopped?
Yes, you can suspend and resume later. The goal of transplantation in chronic enteropaths is to rebalance the microbiome, which must be accompanied by a general rebalancing of the organism, therefore the transplant must be seen in a long-term perspective. - How should the capsules be stored?
The capsules are stored at −80 °C until shipment. Once delivered, they should be stored at room temperature, protected from light and moisture, for the duration of the treatment cycle (30 days), in the container provided with the desiccant. - Are there any side effects?
Rarely diarrhea, vomiting, flatulence, abdominal pain that resolve on their own in 24-48 hours, in case suspend for 3-4 days. - Is one treatment enough?
It depends on the case, there are situations in which there is an improvement immediately, others in which it arrives even after the end of the transplant; the improvement may be definitive or there may be relapses that require more cycles to arrive at a stable resolution of symptoms. In some cases, no improvement in symptoms is seen. Today no one can say a priori how long it will take, how many treatments will be needed, but a light can be glimpsed (see the paper on ulcerative colitis in humans in which a treatment with capsules has been done for 56 consecutive weeks), and the Pet FMT Project can make its contribution. - How to request a Pet FMT Kit?
If you are not registered, contact us using the form below. If you are already registered, you can request the kit using this page.
Fill out the form below 80% of patients respond positively!
Join us! Save your patients from unnecessary suffering and contribute to research.
By selecting Info, you will receive:
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To get started: receive the documentation to join the Pet FMT Project and access fecal microbiota transplantation.
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FMT Mini Guide: "10 Things You Need to Know About Fecal Transplant in Dogs and Cats," a PDF that covers the key concepts of fecal transplantation.
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FMT Clinical Cases: links to webinars in which veterinarians who have used fecal microbiota transplantation share their experience.
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FMT Report: example of a fecal microbiota transplantation report
Call Me: If you wish, we can arrange a zoom call. Write a couple of availabilities in the notes.
